Structure and function of dynamic chromatin organization
Prof. Geneviève Almouzni is Director of the Cancer Research Center Institut Curie, Paris (FR).
She is head of the Nuclear Dynamics and Genome plasticity unit and group leader of the chromatin dynamics team. She obtained her PhD at Pierre-et-Marie-Curie University (FR), worked as postdoctoral fellow at the National Institutes of Health Research Center in Bethesda (USA) in the lab of Prof. Alan Wolffe. She has been CNRS Research Director since January 2000. In 2013, she was awarded the FEBS | EMBO Women in Science Award. She was scientific coordinator of the EU Network of Excellence EpiGeneSys.
- Filipescu D, Naughtin M, …Almouzni G: Genes Dev. 31: 463-480 (2017)
- Muller S and Almouzni G: Nat Rev Genet 18: 192-208 (2016)
- Orsi GA, Naughtin M, Almouzni G: Cell Stem Cell. 19: 567-568 (2016)
Implications of transcriptional mechanism for cell decision-making
Prof. Jonathan Chubb is a Welcome Senior Fellow at the MRC Laboratory for Molecular Cell Biology, University College London
His group would like to understand how cells make choices about their fates. To achieve this, they take the view that one needs to observe the gene expression of individual cells before and during the decision-making process, to test how initial cell "state" maps onto final cell fate. In particular, his group develop and use approaches to image the transcription of genes in living cells.